02/ 2021 – Praxis Priv. Doz. Dr. med. Ramos Lopez
06/ 2020 – 01/ 2021 Praxis Dr. Fink / Consult GmbH
01/ 2015 – 06/ 2020 Diabetes, Cardiovaskulär und Metabolismus in Sanofi
06/ 2002 – 12/ 2014 Medizinischen Klinik 1 – Gastroenterologie, Hepatologie, Pneumologie, Endokrinologie und Diabetologie, Universitätsklinikum Frankfurt am Main (Direktor: Prof. Dr. S. Zeuzem)

Fachärztin für Innere Medizin, Endokrinologie und Diabetologie
Zusatzbezeichnung Ernährungsmedizin der Landesärztekammer Hessen
Laborleiterin des Labors für Molekularendokrinologie der Medizinischen Klinik I, Endokrinologie und Diabetologie

Habilitation: Funktionelle Auswirkung von Genvarianten im Vitamin D System auf die Entstehung des Typ 1 Diabetes

Forschungsrotation (Patenschaftsmodell) an das Institut für Allgemeine Pharmakologie und Toxikologie (Direktor Prof. J. M. Pfeilschifter) des Klinikum der Johann Wolfgang Goethe Universität, Frankfurt am Main

Forschungsaufenthalt in der Institute for Allergy and Immunology (Arbeitsgruppe von Prof. M. von Herrath), San Diego, CA, USA

Promotion Genetische Polymorphismen der CYP27B1 und CYP24 Hydroxylasen als Prädispositionsfaktoren für Autoimmunendokrinopathien (summa cum laude)

Ärztliche Approbationen
mexikanische ärztliche Approbation
deutsche ärztliche Approbation

2012 Forschungspreis der Deutschen Gesellschaft für Vitamine

2010 Innovationspreis des Klinikums der Johann Wolfgang Goethe Universität, Frankfurt am Main

2009 Paul und Ursula Klein-Stiftung des Klinikums der Johann Wolfgang Goethe Universität, Frankfurt am Main

2008 Paul und Ursula Klein-Stiftung des Klinikums der Johann Wolfgang Goethe Universität, Frankfurt am Main

2008 MSD-Stipendium Diabetologie

2007 Else-Kröner-Fresenius-Stiftung – Mehr lesen…

2006 Nachwuchsförderung des Klinikums der Johann Wolfgang Goethe Universität, Frankfurt am Main

2006 Promotionspreis der Alumni des Fachbereichs Medizin

2005 Patenschaftsmodell des Klinikums der Johann Wolfgang Goethe Universität, Frankfurt am Main

2005 Nachwuchspreis der Sektion Angewandte Endokrinologie (SAE) der Deutschen Gesellschaft für Endokrinologie

Buchkapitel

Innere Medizin, Vitamin D-Stoffwechsel, Störungen. E. Ramos-Lopez und K. Badenhoop. Springer-Verlag Berlin Heidelberg 2019

Innere Medizin, Vitamin D-Stoffwechsel, Störungen. E. Ramos-Lopez und K. Badenhoop. Springer-Verlag Berlin Heidelberg 2015

Klassifikation und Genetik, Diabetologie in Klinik und Praxis. K. Badenhoop, E. Ramos-Lopez und P. Weyrich. 6. Auflage. 2010

Publikationen

1. Fox H, Seeger FH, von Quernheim QF, Ramos Lopez E. Vitamin D gene polymorphisms and risk of acute cardiovascular events. Clinical Epidemiology and Global Health. 2020
2. Mauf S, Penna-Martinez M, Jentzsch T, Ackermann H, Henrich D, Radeke HH, Brück P, Badenhoop K, Ramos-Lopez E. Immunomodulatory effects of 25- hydroxyvitamin D3 on monocytic cell differentiation and influence of vitamin D3 polymorphisms in type 1 diabetes.J Steroid Biochem Mol Biol. 147C:17-23; 2015
3. Penna-Martinez M, Epp F, Kahles H, Ramos-Lopez E, Hinsch N, Hansmann ML, Selkinski I, Grünwald F, Holzer K, Bechstein WO, Zeuzem S, Vorländer C, Badenhoop K. FOXE1 association with differentiated thyroid cancer and its progression. Thyroid. 24(5):845-851; 2014
4. Urbschat A, Paulus P, von Quernheim QF, Brück P, Badenhoop K, Zeuzem S, Ramos-Lopez E. Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma. Eur J Clin Invest. 43(12):1282-1290; 2013
5. Strobel F, Reusch J, Penna-Martinez M, Ramos-Lopez E, Klahold E, Klepzig C, Wehrle J, Kahles H, Badenhoop K. Effect of a randomised controlled vitamin D trial on insulin resistance and glucose metabolism in patients with type 2 diabetes mellitus. Horm Metab Res. 46(1):54-58; 2014
6. Morán-Auth Y, Penna-Martinez M, Shoghi F, Ramos-Lopez E, Badenhoop K. Vitamin D status and gene transcription in immune cells. J Steroid Biochem Mol Biol. 136:83-85; 2013
7. Rose K, Penna-Martinez M, Klahold E, Kärger D, Shoghi F, Kahles H, Bayer M, Hintermann E, Pfeilschifter JM, Badenhoop K, Ramos-Lopez E, Christen U. Influence of the vitamin D plasma level and vitamin D-related genetic polymorphisms on the immune status of patients with type 1 diabetes: a pilot study. Clin Exp Immunol. 171(2):171-185; 2013
8. Penna-Martinez M, Ramos-Lopez E, Stern J, Kahles H, Hinsch N, Hansmann ML, Selkinski I, Grünwald F, Vorländer C, Bechstein WO, Zeuzem S, Holzer K, Badenhoop K. Impaired vitamin D activation and association with CYP24A1 haplotypes in differentiated thyroid carcinoma. Thyroid. 22(7):709-716; 2012
9. Brück P, Pierzchlewska M, Kaluzna-Oleksy M, Ramos Lopez E, Rummel M, Hoelzer D, Böhme A. Dying of hematologic patients–treatment characteristics in a German University Hospital. Support Care Cancer. 20(11):2895-902; 2012
10. Cooper JD, Smyth DJ, Walker NM, Stevens H, Burren OS, Wallace C, Greissl C, Ramos-Lopez E, Hyppönen E, Dunger DB, Spector TD, Ouwehand WH, Wang TJ, Badenhoop K, Todd JA. Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes. Diabetes. 60(5): 1624-1631; 2011
11. Lange CM, Bojunga J, Ramos-Lopez E, von Wagner M, Hassler A, Vermehren J, Herrmann E, Badenhoop K, Zeuzem S, Sarrazin C. Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy. J Hepatol. 54(5):887-93; 2011
12. Brück P, Bartsch W, Sadet D, Penna-Martinez M, Kurylowicz A, Bednarczuk T, Paunkovic J, Böhme A, Badenhoop and Ramos-Lopez E. A CXCL10 polymorphism as a marker to predict severity to Graves´ disease. Thyroid. 20(3): 343-345; 2010
13. Ramos-Lopez E, Lange B, Penna-Martinez M, Brück P, Swiech K, Mauf S, Kahles H, Badenhoop K. The role of cubilin gene polymorphisms and their influence on 25(OH)D3 and 1,25(OH)2D3 plasma levels in type 1 diabetes patients. J Steroid Biochem Mol Biol 121 (1-2): 442-444; 2010
14. Badenhoop K, Kahles H, Seidl C, Kordonouri O, Ramos-Lopez E, Walter M, Rosinger S, Ziegler A, Böhm BO; Diabetes Genetics Consortium. MHC- environment interactions leading to type 1 diabetes: feasibility of an analysis of HLA DR-DQ alleles in relation to manifestation periods and dates of birth. Diabetes Obes Metab (2) 1:88-91; 2009
15. Penna-Martinez M, Ramos-Lopez E, Robbers I, Kahles H, Hahner S, Willenberg H, Reisch N, Seidl C, Segni M and Badenhoop K. The rs1990760 polymorphism within the IFIH locus is not associated with Graves´ disease, Hashimoto´s thyroiditis and Addison´s disease. BMC Med Genet. 4(10):126; 2009
16. Penna-Martinez M, Ramos-Lopez E, Stern J, Hinsch N, Hansmann ML, Selkinski I, Grünwald F, Vorländer C, Wahl RA, Bechstein WO, Zeuzem S, Holzer K, Badenhoop K. Vitamin D receptor polymorphisms in differentiated thyroid carcinoma. Thyroid 19(6):623-628; 2009
17. Brück P, Bartsch W, Penna-Martinez M, Kahles H, Seidl C, Böhme A, Badenhoop K, Ramos-Lopez E. Polymorphisms of CXCR3-binding chemokines in type 1 diabetes. Hum Immunol 70 (7): 552-555; 2009
18. Ramos-Lopez E*, Scholten F*, Aminkeng F, Wild C, Kalhes H, Seidl C, Tonn T, Van der Auwera B, Badenhoop K. Association of KIR2DL2 polymorphism rs2756923 with type 1 diabetes and preliminary evidence for lack of inhibition through HLA-C1 ligand binding. Tissue Antigens 73 (6): 599-603; 2009
19. Ramos-Lopez E, Lange B, Kahles H, Willenberg H, Meyer G, Penna-Martinez M, Reisch Nicole, Hahner Stefanie, Seissler J and Badenhoop K. Insulin gene polymorphisms in type 1 diabetes, Addison’s disease and the polyglandular autoimmune syndrome type II. BMC Med Genet 11;9:65; 2008
20. Ramos-Lopez E, Kahles H, Weber S, Kukic A, Penna-Martinez M, Badenhoop K and Louwen F. Gestational diabetes mellitus and vitamin D deficiency: genetic contribution of CYP27B1- and CYP2R1-polymorphisms. Diabetes Obes Metab 10 (8): 683-685; 2008
21. Brück P, Ramos-Lopez E, Batsch W, Böhme A and Badenhoop K. TIM-3 polymorphisms in type 1 diabetes families. J Hum Genet 53 (6): 559-564; 2008
22. Ramos-Lopez E, Fernandez-Balsells M, Kahles H, Seidl C, Ferrer J and Badenhoop K..HLA-DQ haplotypes in Spanish and German families with Graves’s disease: contribution to DQA1*0501-DQB1*0301 mediated genetic susceptibility from fathers. Thryoid 17(11):1131-1135; 2007
23. Ramos-Lopez E, Brück P, Jansen T, Herwig J, Badenhoop K. CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and their vitamin D levels in Germans. Diabetes Metab Res Rev 23(8):631-636; 2007
24. Bailey R, Cooper JD, Zeitels L, Smyth DJ, Yang JH, Walker NM, Hyppönen E, Dunger DB, Ramos-Lopez E, Badenhoop K, Nejentsev S, Todd JA. Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes. Diabetes 56(10):2616-2621; 2007
25. van Etten E, Verlinden L, Giulietti A, Ramos-Lopez E, Branisteanu DD, Ferreira G, Overbergh L, Verstuyf A, Bouillon R, Roep BO, Badenhoop K and Mathieu C. The vitamin D receptor gene FokI polymorphism: functional impact on the immune system. Eur J Immunol 37 (2) 395-405; 2007
26. Ramos-Lopez E, Brück P, Jansen T, Pfeilschifter JM, Radeke HH, Badenhoop K. CYP2R1-, CYP27B1- and CYP24-mRNA expression in German type 1 diabetes patients. J Steroid Biochem Mol Biol 103(3-5):807-10; 2007
27. Ramos-Lopez E, Jansen T, Ivaskevicius V, Kahles H, Klepzig C, Oldenburg J and Badenhoop K. Protection from type 1 diabetes by vitamin D receptor haplotypes. Ann N Y Acad Sci 327-334; 2006
28. Kurylowicz A, Ramos-Lopez E, Bednarczuk T, Badenhoop K. Vitamin D-binding protein (DBP) gene polymorphism is associated with Graves‘ disease and the vitamin D status in a Polish population study. Exp Clin Endocrinol Diabetes. 114(6):329-335; 2006
29. Ramos-Lopez E*, Ghebru S*, Van Autreve J, Aminkeng F, Herwig J, Seifried E, Seidl C, Van der Auwera B, Badenhoop K. Neither an intronic CA repeat within the CD48 gene nor the HERV-K18 polymorphisms are associated with type 1 diabetes. Tissue Antigens 68 (2) 147-152; 2006
30. Kahles H*, Ramos-Lopez E*, Lange B, Zwermann O, Reincke M, Badenhoop K. Sex specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto’s thyroiditis or Addison’s disease in the German population. Eur J Endocrinol 153 (6) 895-899; 2005
31. Ramos-Lopez E, Kurylowicz A, Bednarczuk T, Paunkovic J, Usadel KH, Badenhoop K. Vitamin D receptor polymorphisms are associated with Graves’ disease in German and Polish but not in Serbian patients. Thyroid 15 (10) 1125-1130; 2005
32. Brück P, Wassmann B, Ramos-Lopez E, Hoelzer D, Ottmann OG. Development of hygromas or severe edema during treatment with the tyrosine kinase inhibitor STI571 is not associated with platelet-derived growth factor receptor (PDGFR) gene polymorphisms. Leuk Res 28(11): 1153-1157; 2004
33. Ramos Lopez E, Zwermann O, Segni M, Meyer G, Reincke M, Seissler J, Herwig J, Usadel KH, Badenhoop K. A promoter polymorphism of the CYP27B1 gene is associated with Addison’s disease, Hashimoto’s thyroiditis, Graves‘ disease and type 1 diabetes mellitus in Germans. Eur J Endocrinol 151(2): 193-197; 2004
34. Ramos-Lopez E, Regulla K, Pani MA, Krause M, Usadel KH, Badenhoop K. CYP27B1 polymorphisms variants are associated with type 1 diabetes mellitus in Germans. J Steroid Biochem Mol Biol 89-90(1-5): 155-157; 2004
35. Renne C*, Ramos-Lopez E*, Steimle-Grauer SA*, Ziolkowski P, Pani MA, Luther C, Holzer K, Encke A, Wahl RA, Bechstein WO, Usadel KH, Hansmann ML, Badenhoop K. Thyroid fetal male microchimerisms in mothers with thyroid disorders: presence of Y-chromosomalimmunofluorescence in thyroid- infiltrating lymphocytes is more prevalent in Hashimoto’s thyroiditis and Graves‘ disease than in follicular adenomas. J Clin Endocrinol Metab 89(11): 5810-5814; 2004